//www.igerbera.com/journals/jamacardiology en-us Wed, 01 Mar 2023 00:00:00 GMT Wed, 08 Mar 2023 11:44:03 GMT Silverchair jamams@jamanetwork.org support@www.igerbera.com //www.igerbera.com/journals/jamacardiology/fullarticle/2802487 Wed, 01 Mar 2023 00:00:00 GMT Mission Statement: JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy. Health equity, especially when supported by original science, is a leading editorial priority. 8 3 212 212 10.1001/jamacardio.2022.3428 2802487 //www.igerbera.com/journals/jamacardiology/fullarticle/2801112 Wed, 01 Mar 2023 00:00:00 GMT This cohort study assesses the association between change in N-terminal pro–B-type natriuretic peptide with risk for incident heart failure and death. 8 3 222 230 10.1001/jamacardio.2022.5309 2801112 //www.igerbera.com/journals/jamacardiology/fullarticle/2801004 Wed, 01 Mar 2023 00:00:00 GMT This post hoc analysis of a randomized clinical trial examines data for patients according to the New York Heart Association class of their heart failure symptoms at baseline to evaluate the health status benefit of tafamidis vs placebo. 8 3 275 280 10.1001/jamacardio.2022.5251 2801004 //www.igerbera.com/journals/jamacardiology/fullarticle/2801003 Wed, 01 Mar 2023 00:00:00 GMT This case report describes a diagnosis of quadricuspid aortic valve in a man in his 30s with a history of splenic infarct who presented with right-sided ischemic stroke. 8 3 298 298 10.1001/jamacardio.2022.4603 2801003 //www.igerbera.com/journals/jamacardiology/fullarticle/2801002 Wed, 01 Mar 2023 00:00:00 GMT This genetic association study evaluates the association of protein-truncating variants in APOB and PCSK9 with low-density lipoprotein (LDL) cholesterol levels and coronary heart disease. 8 3 258 267 10.1001/jamacardio.2022.5271 2801002 //www.igerbera.com/journals/jamacardiology/fullarticle/2801001 Wed, 01 Mar 2023 00:00:00 GMT This randomized clinical trial assesses the effects of a moderately accelerated personalized backup heart rate compared with 60 bpm in patients with heart failure with preserved ejection fraction (HFpEF) who have preexisting pacemaker systems that limit pacemaker-mediated dyssynchrony. 8 3 213 221 10.1001/jamacardio.2022.5320 2801001 //www.igerbera.com/journals/jamacardiology/fullarticle/2801000 Wed, 01 Mar 2023 00:00:00 GMT This narrative review discusses the model selection and evaluation process with respect to prediction accuracy when the outcome of interest is timing of a cardiovascular event. 8 3 290 295 10.1001/jamacardio.2022.5279 2801000 //www.igerbera.com/journals/jamacardiology/fullarticle/2800879 Wed, 01 Mar 2023 00:00:00 GMT To the Editor In a recent multicenter investigation, Hillerson et al highlighted important disparities in ST-segment elevation myocardial infarction management between those residing in rural vs urban settings. The lack of observed differences in outcome measures among these settings, despite the measured variations in process metrics, is encouraging and may be an indicator of progress in providing equitable care in hospitals. However, the probable exposure misclassification raises concerns regarding the internal validity of the results. I commend the authors for appreciating the limitations of their analysis, yet the definition of rurality applied should be further recognized given the importance of rural-urban dichotomization in the study design. 8 3 301 301 10.1001 / jamacardio.2022.5218 2800879 //www.igerbera.com/journals/jamacardiology/fullarticle/2800878 Wed, 01 Mar 2023 00:00:00 GMT 科恩在回复我们感激我们的艺术的兴趣icle. In our work comparing the process of care and the hospital outcomes of urban vs rural patients with ST-elevation myocardial infarction (STEMI), we used the data elements collected in the National Cardiovascular Data Registry Chest Pain–MI Registry. In that registry, rurality is defined on the basis of the zip code of the patient’s home address. The US Office of Management and Budget (OMB) cutoff of statistical urbanized areas being those with a minimum population of 50 000. The OMB population data are derived from the US Census county-level data. When zip codes are used for rural vs urban designation, they are approximations of the urbanized areas as defined by the OMB. 8 3 301 302 10.1001/jamacardio.2022.5221 2800878 //www.igerbera.com/journals/jamacardiology/fullarticle/2800877 Wed, 01 Mar 2023 00:00:00 GMT 这对参与者f队列研究分析数据rom the Southern Community Cohort Study to determine whether rurality is associated with increased risk of heart failure and whether rurality-associated risk varies by race and sex. 8 3 231 239 10.1001 / jamacardio.2022.5211 2800877 //www.igerbera.com/journals/jamacardiology/fullarticle/2800308 Wed, 01 Mar 2023 00:00:00 GMT This cohort study performs a post hoc analysis of data for US and Australian participants in the Aspirin in Reducing Events in the Elderly (ASPREE) clinical trial to determine the association between level of high-density lipoprotein cholesterol and increased fracture risk in healthy older adults. 8 3 268 272 10.1001/jamacardio.2022.5124 2800308 //www.igerbera.com/journals/jamacardiology/fullarticle/2800306 Wed, 01 Mar 2023 00:00:00 GMT In the study by Hussain et al, published in this issue of JAMA Cardiology, the authors used the Aspirin in Reducing Events in the Elderly (ASPREE) trial in a post hoc analysis to conduct an observational study assessing the associations between high-density lipoprotein cholesterol (HDL-C) at baseline and risk of fracture during the trial period during which individuals were randomized to aspirin vs placebo for primary prevention of cardiovascular events. The study cohort included over 16 000 healthy participants 70 years and older and analyzed 1659 fractures over a median follow-up of 4 years. They found that higher HDL-C at baseline was associated with an increased fracture risk, independent of other risk factors. Given the well-known inverse associations between HDL-C and heart disease, these findings suggest inconsistencies in the epidemiology of HDL-C and suggest the provocative question as to whether high HDL-C could be a useful biomarker for identifying those at risk for fractures. 8 3 273 274 10.1001/jamacardio.2022.5143 2800306 //www.igerbera.com/journals/jamacardiology/fullarticle/2800305 Wed, 01 Mar 2023 00:00:00 GMT This study examines the effect of mavacamten on exercise physiology using cardiopulmonary exercise testing. 8 3 240 247 10.1001/jamacardio.2022.5099 2800305 //www.igerbera.com/journals/jamacardiology/fullarticle/2800013 Wed, 01 Mar 2023 00:00:00 GMT The SIMULATOR study was a French trial performed in 42 university centers where fellows who were inexperienced in transesophageal echocardiogram (TEE) were randomized to simulation-based vs traditional teaching on TEE knowledge and skills. Authors measured theoretical and practical scores 3 months after training, as well as TEE duration and fellows’ self-perceived preparedness to perform a TEE. Fellows in the simulation group were noted to have higher scores, shorter times to TEE completion, and more confidence in performing a TEE. The effectiveness of simulation training was noted to have the greatest impact on fellows who were less than 2 years into training. The study by Pezel et al is a welcome addition to the simulation literature in the cardiology space, noteworthy for its randomized and multicenter design, feats rarely achieved in medical education scholarship. The authors should be congratulated both for executing a multisite study focused on optimizing medical education and for completely standardizing teaching of skills across sites. Notably, it is the largest TEE simulation study to date. 8 3 256 257 10.1001/jamacardio.2022.5030 2800013 //www.igerbera.com/journals/jamacardiology/fullarticle/2800012 Wed, 01 Mar 2023 00:00:00 GMT This cross-sectional study estimates out-of-pocket costs of heart failure with reduced ejection fraction medication regimens in Medicare Part D under current law and the Inflation Reduction Act. 8 3 299 301 10.1001/jamacardio.2022.5033 2800012 //www.igerbera.com/journals/jamacardiology/fullarticle/2800011 Wed, 01 Mar 2023 00:00:00 GMT This study attempts to assess the effectiveness of simulation-based vs traditional teaching of transesophageal echocardiography knowledge and skills of cardiology fellows. 8 3 248 256 10.1001/jamacardio.2022.5016 2800011 //www.igerbera.com/journals/jamacardiology/fullarticle/2799973 Wed, 01 Mar 2023 00:00:00 GMT This narrative review describes options for the management of severe aortic valve disease in adults younger than 65 years and offers a framework for shared decision-making relative to different sets of complications and long-term considerations. 8 3 281 289 10.1001/jamacardio.2022.4770 2799973 //www.igerbera.com/journals/jamacardiology/fullarticle/2799722 Wed, 01 Mar 2023 00:00:00 GMT A man in his mid-50s with a medical history of nonspecific T-wave abnormalities on electrocardiogram reported new-onset chest discomfort, diaphoresis, and shortness of breath that woke him from sleep. Emergency medical services found him to be in a wide complex tachycardia. What would you do next? 8 3 296 297 10.1001/jamacardio.2022.4888 2799722

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