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这个随机临床试验检查addition of treatment with liposomal irinotecan to fluorouracil and leucovorin for patients with advanced biliary tract cancer.

This randomized clinical trial compares exemestane, 25 mg, given once daily, 3 times weekly, and once weekly for the treatment of estrogen receptor–positive breast cancer in postmenopausal women prior to surgery.

This cohort study investigates clinicopathologic and prognostic associations of hypercalcemia in patients with intrahepatic or extrahepatic cholangiocarcinoma.

This cross-sectional study compares rates of subcutaneous and intravenous administration of medications and fluids among patients with cancer in 2 acute palliative care units in the US and Canada.

This phase 2 randomized clinical trial evaluates whether the addition of vistusertib to weekly paclitaxel improves clinical outcomes in patients with platinum-resistant ovarian high-grade serous carcinoma.

This nonrandomized clinical trial investigates the addition of pembrolizumab to ifosfamide, carboplatin, and etoposide chemotherapy and evaluates the response rate of patients with relapsed or refractory Hodgkin lymphoma.

A 76-year-old woman presents with a palpable left axillary mass, yet no breast lesions are found. What is your diagnosis?

This nonrandomized clinical trial assesses the recommended phase 2 dose of regorafenib, ipilimumab, and nivolumab immunotherapy for patients with refractory microsatellite stable metastatic colorectal cancer.

This randomized clinical trial examines the effect of adding fulvestrant to alisertib on objective tumor response rates in endocrine-resistant metastatic breast cancer.

This Viewpoint discusses the role of data interpretation and clinical trial design in improving therapy of neuroendocrine cancers.

This systematic review meta-analysis investigates the comparative effectiveness of triplet therapy vs androgen pathway inhibitors doublet therapy for patients with heterogeneous metastatic castration-sensitive prostate cancer.

This cohort study evaluates whether racial and ethnic disparities in incidence of triple-negative breast cancer among US women vary across states.

This cross-sectional study examines the rate of HPV vaccination and the number eligible for this vaccination among younger veterans and civilians.

This Viewpoint discusses firearm safety guidelines among patients diagnosed with cancer and at a higher risk of suicide.