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This Viewpoint discusses serious adverse events linked to interactions between therapists and patients in trials of psychedelic-assisted therapy.

This systematic review and meta-analysis investigates the emotion processing, reward processing, and working memory brain domains of individuals with bipolar disorder vs those of healthy control individuals.

This cohort study evaluates neurobiological, psychosocial, and behavioral mechanisms potentially underlying associations between physical activity and psychiatric symptoms in children in the Netherlands.

This case-control study investigates the association between nonoptimum temperature and suicide death in a warming climate.

This cohort study examines the association of the receipt of telehealth services and medications for opioid use disorder (OUD) with fatal drug overdoses before and during the pandemic.

This study uses data from the US Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research database to assess 20-year trends in drug overdose fatalities among older adults in the US.

This Viewpoint examines the scarcity of psychiatric success rate trend data and discusses what can be done about it.

This randomized clinical trial evaluates whether practitioner-supported mindfulness-based cognitive therapy self-help is superior to practitioner-supported cognitive behavioral therapy self-help at reducing depressive symptom severity at 16 weeks postrandomization among patients with mild to moderate depression.

This cross-sectional study examines ophthalmic data, including imaging results, for 101 416 patients from the AlzEye study to determine the association between retinal biomarkers and schizophrenia.

This cross-sectional study characterizes factors associated with the direct addition of buprenorphine to urine specimens in individuals prescribed buprenorphine for opioid use disorder.

This Viewpoint proposes a model of cannabis use disorder diagnosis in the context of cannabis for therapeutic purposes that is based onDSM-5model of diagnosing substance use disorder in the context of prescribed medication use

This time-series analysis assesses the association of implementation of postoverdose outreach programs with opioid fatality rates in Massachusetts municipalities with high numbers of opioid-related medical emergency services responses.

This systematic review and meta-analysis assesses the prevalence of depression among individuals living in low- and middle-income countries during pregnancy and up 1 year post partum.

This cohort study investigates the association between antidepressant fill trajectories during pregnancy and postpartum psychiatric outcomes in Denmark and Norway.

This Special Communication discusses the potential for individuals with unusual beliefs and experiences to provide adversarial examples in generative modeling approaches to understanding delusions and hallucinations in psychotic illness.

This study examines the associations of 24/7 sobriety programs with reduced alcohol-involved offenses.